Mudzini School is located 18 km north of Nyali Centre at the Kikambala area between Mombasa island and Kilifi town. It is 19 Km from Kilifi bridge and 1 km off of Mombasa Malindi road highway near Sultan Palace and Pwani Oil.
Major landmarks also include Sun and Sand hotel, Sultan Palace and Vipingo ridge. The school is accessible through a supervised entrance gate. Cars access the school along a road opposite Pwani Oil entrance along Mombasa Malindi Road.
The school has a full time 24 hour seven days a week security service. The recreation areas are completely enclosed thus offering maximum protection for students.